Assessment 1 Literature Review Breakdown
Assessment 1 Literature Review Breakdown
Section & Word Limit
(3,000) Marks Description
Title 5 Scientific title that is descriptive and accurately relates to content
The reader should know exactly what to expect
Intro
500 20 Description of gene therapy; brief introductory overview of gene therapy
Outline details of the body text; sets scene of essay and introduce main points and objectives; indicate material you will cover
Outline necessary background information such as disease characteristics and gene delivery systems (all or some?); brief characteristics of the disease your essay is focusing on; characteristics of the gene delivery systems
Approx 1 paragraph
Discussion
2,000 40 Focus on a particular clinical area of your choice; e.g. Cancer, neurological disease, hereditary metabolic diseases
Clear links to published works; interprets the data correctly and shows clearly a link between gene therapy/ies and condition(s).
Consider the gene therapy approaches that have been previously used to treat disease in animal models and/or human clinical trials.
Providing information as to what you consider are landmark discoveries in the area; e.g. research that had a major impact on your chosen field, for example an improved gene delivery system that dramatically improved clinical outcome in patients or animal models.
Try and discuss the findings of your literature review by contrasting results of different research e.g., In paper X McGonigle et. al demonstrated Y results or outcome, however these results were in contrast to McDuff et al who showed opposite results.
When comparing research findings, highlight what you perceive as weaknesses or strengths in the work.
If possible give a brief historical perspective e.g. how developments in your chosen area have changed/improved over time
Conclusion
500 15 Summarise and highlight the main points of the articles; this should be succinct and clear.
Explain future directions of this research area
One paragraph
References 10 Style applied consistently, Harvard or APA
Accurate references with 8 appropriate references
Quality of references will be assessed
References on last page or two
5 primary sources
Case reports from the past 7 years
Grammar, Layout, Accuracy 10 Excellent grammar, style and accuracy. Fluent writing style appropriate to document. Grammar and spelling mostly accurate (<5 mistakes).
The material is carefully and logically structured resulting in clarity of information and message.
Gene Therapyis important area in modern medical research. Choose one clinical area of gene therapy research for your essay and undertake literature searches for information on the developments, status and challenges on your chosen topic. If you wish you may compare the gene therapy approaches with other treatment modalities.
You may either cover a broad area in a category (e.g. gene therapy research for cancers) or be more specific in your approach (e.g. gene therapy research for a specific genetic disorder). If you are unsure about your choice of topic, please email it through and I am happy to provide you guidance.
Gene Therapy is an important area in modern medical research providing novel therapeutic approaches to treat disease. Gene therapy can be categorised in terms of viral or non-viral, use of nanomaterials and biomaterials which complex nucleic acids and allow delivery to the host, using an in vivo or ex-vivo approach. In this assessment you should choose one clinical area of gene therapy research for your essay and undertake literature searches for information on the developments, status and challenges on your chosen topic. You can also compare the gene therapy approaches with other treatment modalities.
Text should be word-processed, with appropriate layout and use of headings/sub-headings. Font and line spacing are not part of the assessment criteria, listed below.
You may choose to use subheadings for a logical structure.
Diagrams should can be used to illustrate specific aspects - (please ensure that you correctly cite/reference all sources of diagrams used, unless they are original and composed by you, since this is an important aspect of academic integrity).
Please avoid images with very large file sizes, as this will make your essay too large to upload/download (save any images as lower resolution, to decrease the file size).
