The Public Health Service Syphilis Study (1932-1971)
The Public Health Service Syphilis Study (1932-1971)
The study involving 400 poor black men in rural Alabama initially designed to study syphilis.
The study continued to track these men until 1972 when the first public accounts of the study appeared in the national press.
Public was outraged.
The study resulted in 28 deaths, 100 cases of disability, 40 wives had been infected, and 19 cases of congenital syphilis.
In 1973, Fred Gray filed a $1.8 billion lawsuit against the GovernmentGovernment settled out of court for $10 million1994 President Clinton formally apologized to the survivors and the familiesWhat were some of the ethical problems? (list and explain at least 8 items)
2.What is the Belmont Report?
3. List & Describe the three basic principles associated with The Belmont Report
4. A randomized controlled trial is conducted to evaluate the incidence of diarrhea in 300 children with otitis media treated with a broad-spectrum antibiotic, amoxicillin + clavulanic acid, compared to amoxicillin. During the study, the participants and the investigator were not aware of the treatment allocation between experimental and control groups.
This study is:
Open-label
Single-blinded
Double-blinded
Non-blinded
The study design described above reduces:
Adverse drug reactions
Degree of bias
Compliance to the study protocol
Drop-out rate of participantsDuration of the study
Classify the following variables (specify the type of numerical and categorical data)?
Example: Numerical, Discrete: Number of cigarettes smoked per day.
1. Grade point average (on a scale of 0-4):
2. A persons occupation:
3. Marital status:
4. A persons height (in inches):
5. Number of children in a family:
6. Type of newspaper read:
7. Hair color:
8. Pulse rate (beats per minute):
9. Size of a cars gas tank (in liters):
10. Weight (in pounds):
11. Computer skill level (novice, intermediate, expert):
12. The number of words per minute that a person can type:
13. The level of lead in water (milligrams per liter):
14. First letter of your last name:
15. Serum cholesterol level:
16. Outcome when tossing a coin (heads or tails):
17. Letter grade in a course (A, B, C, F):
18. Number of goals scored in a hockey game:
19. Time (in hours):
20. Five years survival after chemotherapy:
Apply basic and advanced search. Illustrate your results from PubMed or other databases (make a screenshot of pages with search results).
- by using three Boolean operators AND, OR, NOT:
- by using specifying filters:
