Clinical Biochemistry and Pathophysiology BIOM3202
- Subject Code :
BIOM3202
Assessment details:
- Template to be used to write the report (with some tips to help you prepare the report)
- Marking guide which will be used in the assessment process(with some tips to help you prepare the report)
You are required to write a report (around 1200 to 1,500 words) using a case study approach describing the pathophysiology, specific biochemical profile characteristics observed that led to the provisional diagnosis, differential diagnoses and potential treatment options. You may also recommended further tests that will assist in confirming the diagnosis. Further details on the case, a template and an exemplar will be provided to you on the Moodle site to assist in preparation.
The submitted assessment items must be your own work, and not written, prepared, or composed using Generative AI tools (GenAI/LLM). This includes the manipulation or analysis of images and data.
Note: Cutting and pasting of GenAI/LLM material into assessments may be considered contract cheating and/or plagiarism.
Casestudy1
A59-year-oldmale,Mr.JonesRobert,wasadmittedtotheICUwithaleakingaortic aneurysm. His BP was 110/60 mmHg and pulse rate 107 bpm.
A pre-operative assessment performed 5 days prior revealed normal serum U&Eresults, specifically Urea 5.3 mmol/L and Creatinine 0.09 mmol/L.
TherequestformandhistestresultsonadmissiontoICUareshownbelow.
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BUCKETPATHOLOGYREQUESTFORM |
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Surname |
Robert |
GivenName |
Jones |
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|
Dateofbirth |
18.01.1965 |
URNumber |
9853 |
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|
Gender |
M |
Ward |
ICU |
|||
|
Historyand medication |
Post-operativeleakingaorticaneurysmrepair |
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|
Testsrequested FASTING RANDOM |
Blood-UEC,Osmolality |
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RequestingDrs Name |
Dr.SimonPhilip |
Requesting Drssignature |
Simon |
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CollectionDeclaration:Icertifythatthebloodspecimen(s)accompanyingthisrequestwasdrawnfromthe patient named above and I established the identity of this patient by direct inquiry and/or by inspection of wristband and immediately upon the blood being drawn I labelled the specimen(s). |
||||||
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CollectionDate 14.02.2025 |
Time 07.40 |
Signed:MaryCain |
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SerumBiochemistry:
|
Analyte |
Patientresults |
Referenceranges |
|
Sodium |
147 |
132144mmol/L |
|
Potassium |
4.3 |
3.24.8mmol/L |
|
Chloride |
105 |
98108mmol/L |
|
Bicarbonate |
30 |
2333mmol/L |
|
Aniongap |
16 |
1017mmol/L |
|
Urea |
20.4 |
3.08.0mmol/L |
|
Creatinine |
0.21 |
0.060.12mmol/L |
|
Osmolality |
320 |
275295mosmol/kg |
ThepatientwastransfusedwithseveralunitsofbloodwhichstabilisedhisBP. A urine sample was then collected and the electrolytes analysed
UrineBiochemistry:
|
Urea |
380mmol/L |
|
Creatinine |
6.5mmol/L |
|
Sodium |
49mmol/L |
|
Chloride |
19mmol/L |
|
Osmolality |
504mosmol/kg |
Writeareport(approximately1,500words)onwhatyouthinkJonesscondition/smightbe.
Considertheresultsinrelationtooneanotherandsuggestfurtherteststhatmayhelpin confirming or eliminating differential diagnoses.
Pleasemakesureyouusethecasereporttemplatetowriteyourreport.Thistemplatealso outlines a series of tips to help you structure the report and areas to focus your report on.
Adetailedmarkingrubric&guidehasalsobeenprovidedtoyoutohelpyouinwritingthe report.
Tips:
The total word count for this case study report is between 1200 to 1500
words (excluding references).
Reports should be typed in Word and adhere to the format of the given
template (Arial, 12pt, Single spacing).
The report must include your name and page
numbers should be included in the footer of all pages of the report.
"Be sure to carefully review the rubric for detailed criteria and the
breakdown of marks."
Total marks: 100 marks
Total weighting of this assessment: 20%
Additional Tips
- The report should be written in scientific style. Use the correctterminology where appropriate.
- Avoid using ownership words or starting sentencing with I, we, me,they, you, e.g. dont write I think that.., then I and so on. Instead use statements such as, the results suggest..
- When you are finished, ask someone else to proofread your report and let you know if they understand what you have written. They may give you some suggestions about the clarity and spot some typos you have overlooked! Your practical report should clearly explain the clinical history and reason for testing, as well as, what tests you have performed, why you did those, the results that you obtained, and an explanation of their significance.
Please DO NOT submit a PDF version of your draft assessment on the
forums.
