Question 1D-Dimer is a small protein fragment found in blood that is indicative of blood clotting. A D-dimer concentration above a threshold of 500

Questions

Question 1D-Dimer is a small protein fragment found in blood that is indicative of blood clotting. A D-dimer concentration above a threshold of 500 ng/ml is used to diagnose venous thromboembolism (VTE). It is suspected that in healthy pregnancy D-Dimer levels naturally increase above this threshold, thereby leading to false positive VTE test results. To assess how D-Dimer changes at a population level during healthy pregnancy, 90 healthy pregnant women, from various trimester stages (30 women at trimester 1; 30 women at trimester 2; 30 women at trimester 3), were recruited and their D-Dimer concentrations were measured. The aim of the study is to determine if the mean D-Dimer concentrations differ between the three trimesters of pregnancy. The data for this question can be found in the D-Dimer sheet of your data file. Use the 5% level of significance to answer this question.

Question 2VO2 max is a measure of cardiovascular health. It is the maximum oxygen volume a person can consume while performing intense exercise. For sedentary individuals, it takes approximately 4-6 weeks of training to noticeably increase VO2 max. High-intensity interval training (HIIT) programs are thought to increase VO2 max more quickly.

To determine whether HIIT was capable of increasing VO2 max after only 3 weeks, 25 sedentary males aged 40-49 years were recruited for the study. Their VO2 max was measured at baseline and again after 3 weeks of the training program. The measurements (ml/kg/min) can be found in the VO2 sheet of your data file. Use alpha = 0.01 to answer this question.

Question 3Nitrate is a naturally occurring compound that is found in rivers, lakes, and groundwater. Excess nitrate can enter waterways from sources of human activities such as landfills, urban drainage, and run-off from fertilised soil. High levels of nitrate in drinking water can lead to health problems.

There is evidence to show that surface water nitrate levels fluctuate seasonally during wet and dry seasons; however, the effects of seasonality on ground water remain unclear. To determine whether ground water nitrate levels change seasonally, quarterly water samples were taken from 20 wells and the nitrate levels were measured (mg/L). Use the date in the Nitrate sheet of your data file and alpha = 0.05 to answer this question.

Assignment 1 - Final Submission Only

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Due2 Sepby12:00

Points30

Submittinga file upload

File typesdoc, docx, and pdf

Availableuntil 9 Sep at 12:00

Assignment 1

Value:30%

Group or individual:Individual

Page limit:12 pages (references and rubric are excluded from the page limit)

Unit Learning Outcomes:

Select an appropriate biostatistical methodology to analyse health, biology, and/or environmental data.

Perform commonly used hypothesis tests as appropriate.

Conduct statistical analyses using a specialised software package.

Report statistical findings in a scientific manner.

Feedback:

Download theMAT5212 Assignment Marking RubricDownload MAT5212 Assignment Marking Rubricfor your reference.

Feedback for Assignment 1 will be provided via the following mechanisms:

Global feedback to the entire class. This will cover common issues and areas for improvement. It will be disseminated via a Canvas Announcement.

Individual feedback: mark-up of therubric. This will be accompanied by a few (5-10) examples noted directly on your assignment.

Individual feedback: a comment from your marker that will identify the 1-2 most important items to focus on for improvement in Assignment 2.

Assignment exemplars (use for the module 3 discussion board activity)

Please download the following two files and use them to complete the Module 3 Discussion Board Activity.

MAT5212 Assignment ExemplarDownload MAT5212 Assignment ExemplarExemplar Similarity ReportDownload Exemplar Similarity ReportAnnotated ExemplarDownload Annotated Exemplar

Assignment template:

For your final submission, please submit your assignment using theassignment templateDownload assignment template file. This file contains the marking rubric and it will facilitate marking in the online system.Please note:when submitting your final assignment, the plagiarism detection software will flag the entire marking rubric. As a result, your similarity score will be artificially inflated. I recommend that you prepare a draft of your assignment on a separate document and submit it to thePre-submission Plagiarism Checklink.

Purpose

This assignment will provide you the opportunity to develop your skills in comparing population means. The assignment covers content up to and including Module 5.

Description

You will perform statistical analysis for all three of the questions below. This will include selecting the most appropriate hypothesis, performing descriptive statistics, stating and checking assumptions, performing appropriate estimations, and performing hypothesis testing (including relevantposthocanalyses, as appropriate). You are not required to provide contextual background information for the questions; your assignment should focus only on the statistical analyses.

You are expected to present your analyses in a scientific manner. This means that figures and tables should be formatted appropriately (with captions/titles and axis labels), and written text should guide your reader through your analyses, justifications, and interpretations.

Note on assumptions: if your assumptions are violated, you may proceed with the most appropriate hypothesis test. If this happens, you are required to report on the potential consequences of the violation and how you would overcome the violation(s) in future practice.

Questions

Question 1D-Dimer is a small protein fragment found in blood that is indicative of blood clotting. A D-dimer concentration above a threshold of 500 ng/ml is used to diagnose venous thromboembolism (VTE). It is suspected that in healthy pregnancy D-Dimer levels naturally increase above this threshold, thereby leading to false positive VTE test results. To assess how D-Dimer changes at a population level during healthy pregnancy, 90 healthy pregnant women, from various trimester stages (30 women at trimester 1; 30 women at trimester 2; 30 women at trimester 3), were recruited and their D-Dimer concentrations were measured. The aim of the study is to determine if the mean D-Dimer concentrations differ between the three trimesters of pregnancy. The data for this question can be found in the D-Dimer sheet of your data file. Use the 5% level of significance to answer this question.

Question 2VO2 max is a measure of cardiovascular health. It is the maximum oxygen volume a person can consume while performing intense exercise. For sedentary individuals, it takes approximately 4-6 weeks of training to noticeably increase VO2 max. High-intensity interval training (HIIT) programs are thought to increase VO2 max more quickly.

To determine whether HIIT was capable of increasing VO2 max after only 3 weeks, 25 sedentary males aged 40-49 years were recruited for the study. Their VO2 max was measured at baseline and again after 3 weeks of the training program. The measurements (ml/kg/min) can be found in the VO2 sheet of your data file. Use alpha = 0.01 to answer this question.

Question 3Nitrate is a naturally occurring compound that is found in rivers, lakes, and groundwater. Excess nitrate can enter waterways from sources of human activities such as landfills, urban drainage, and run-off from fertilised soil. High levels of nitrate in drinking water can lead to health problems.

There is evidence to show that surface water nitrate levels fluctuate seasonally during wet and dry seasons; however, the effects of seasonality on ground water remain unclear. To determine whether ground water nitrate levels change seasonally, quarterly water samples were taken from 20 wells and the nitrate levels were measured (mg/L). Use the date in the Nitrate sheet of your data file and alpha = 0.05 to answer this question.

Data files

A unique data file is assigned to each student. You must use your unique data file to complete your assignment. Please click the link below to find your data file (you will be asked to log in with your ECU credentials). Your data file is named with yourECU username.If your data file is missing, please email your unit coordinator immediately.

MAT5212 Data Files(Links to an external site.)

Assignment Preparation Instructions

Step 1:Get started. Visit the Academic Skills @ECUHow to Write Assignmentspage to guide you in the process. Make sure to also visit theFinding ResourcesandParaphrasingpages to ensure you understand academic integrity expectations.

Step 2:Get organised. Review the marking rubric, identify appropriate resources to reference, and download your unique data file.

Step 3:Read the questions and decide which statistical test is most appropriate to use. Plan and perform your statistical analysis (use the Description section above to guide you).

Step 4:Check your progress regularly. Use the rubric to check your assignment. Submit draft versions of the assignment and review the similarity report. Edit the assignment as necessary.

Need help? Seek help!The School of Science Senior Learning Advisor and Librarian are here to help. Visit the Academic Skills @ECUSchool Specific Supportpage for details.

Submission Instructions

Step 1:SelectStart Assignment(top right corner of this window).

Step 2:In theFile uploadtab, upload a Word or PDF file of your assignment.

Step 3:Read the Student Declaration and tick the box if you are confident the declaration is true and correct.

Step 4:SelectSubmit assignment.

Resources

Library Referencing Guide(Links to an external site.)Academic IntegrityLinks to an external site.Extension Requests(Links to an external site.)

Assessment Declaration

In submitting this work I confirm that:

I have acted withacademic integrityLinks to an external site.in preparing my assignment

I have not engaged in any form ofacademic misconductLinks to an external site.when preparing my assignment

If you are unsure about the academic integrity guidelines,do notsubmit your assignment before speaking with your unit coordinator or ECU learning advisor. When marking assignments, unit staff will assume that you have read the Academic Integrity page inModule 0.